印度代购提示您，本品尼鲁米特主要用于前列腺癌或转移性前列腺癌治疗，一般与手术治疗和化学治疗合并应用。少数患者服用尼鲁米特会出现黑暗中视力调节障碍及色觉障碍，停药后可消失，也可配戴有色眼镜以减轻症状；见戒酒硫样作用；肺间质综合征(用药应慎重)；轻度转氨酶升高，继续用药时可好转，但可能同时发生溶细胞性肝炎；其它可见恶心、呕吐、阳痿、性欲减退、面部潮红等。

Nierumete is mainly used for the treatment of prostate cancer or metastatic prostate cancer, and is generally used in combination with surgery and chemotherapy. A small number of patients taking Nieruimide will appear in the dark vision regulation disorder and color vision disorder, can disappear after stopping the drug, also can wear colored glasses to alleviate the symptoms; See alcohol-sulfur like effect; Interstitial lung syndrome (medication should be cautious); Mild elevation of aminotransferase can be improved with continued medication, but cytolytic hepatitis may occur at the same time; Other visible nausea, vomiting, impotence, loss of sexual desire, facial flushing and so on.

尼鲁米特

　　印度代购提示您，本品尼鲁米特是抗雄性激素的药物，主要用于前列腺癌治疗，由法国研制、推出。 主要作用是与雄性激素的受体结合，阻止雄性激素与相应的受体结合，发挥抗雄性激素作用。但是该品对雌性激素、孕激素、盐或糖皮质激素受体基本无作用，因此减少了抗其他激素的副作用。 尼鲁米特在体内稳定，化学结构很少改变，同受体结合持久，维持作用时间长，不产生雄激素作用。

　　印度代购提示您，本品如同手术或化学去势方法结合，使抗外周雄激素作用更完全。也即能使任何去势方法后肾上腺仍能分泌雄性激素的效应得到抑制，并可抑制LHRH类似物作用后最初几天内出现的睾丸素增加和作用的加强。由此，作用表现较彻底。 尼鲁米特口服给药，吸收迅速而完全，在血液中的药物基本上呈原药，消除半衰期约5-6小时，血浆蛋白结合率约 80-84％，结合在红细胞中的药物占血药的36％。尼鲁米特在肝脏中同葡萄糖醛酸或硫酸结合后经肾由尿排出，尿中原药量少，绝大部分在24小时内排出。连续多次给药，经二周才达到稳态血药浓度，其浓度高低与药量相关，无蓄积作用。

Combined with surgical or chemical castration methods, the anti-peripheral androgen effect is more complete. This inhibits the effect of the adrenal glands still secreting androgens after any castration method and inhibits the increase and enhancement of testosterone that occurs in the first few days after LHRH analogue. Thus, the action is more thorough. Oral administration of nieruimide, absorption is rapid and complete, the drug in the blood is basically the original drug, elimination half-life is about 5-6 hours, the plasma protein binding rate is about 80-84%, the drug binding in red blood cells accounts for 36% of the blood drug. In the liver with glucuronic acid or sulfuric acid combined by urine excretion through the kidney, urine original drug quantity is small, most of the excretion within 24 hours. After repeated administration, steady blood drug concentration was reached after two weeks, and the level of drug concentration was related to drug dosage, without accumulation effect.