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复发或难治性多发性骨髓瘤能用泊马度胺/柏马度胺(POMALYST)吗?

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  印度正品代购提示,泊马度胺(Pomalyst)的安全性和有用性在一项有221名复发或难治性多发性骨髓瘤患者参与的临床实验中进行了评价。该实验的意图是观察经医治后癌症彻底或部分消失的患者数(客观应对率,或ORR)。患者被随机分配承受单独泊马度胺(Pomalyst)或泊马度胺(Pomalyst)加低剂量皮质类固醇地塞米松。

The safety and usefulness of Pomalyst was evaluated in a clinical trial involving 221 patients with relapsed or refractory multiple myeloma. The intent of the trial was to look at the number of patients whose cancer disappeared completely or partially after treatment (objective response rate, or ORR). Patients were randomly assigned to receive Pomalyst alone or Pomalyst plus a low dose of the corticosteroid dexamethasone.

 

泊马度胺

 

  印度正品代购提示,泊马度胺(Pomalyst)是继沙利度胺和来那度胺后的第三个度胺类药物,是一种免疫调节剂,具有抗肿瘤活性,它能按捺造血肿瘤细胞的增殖,并调节多种细胞因子的发生,而且能够增强T细胞和自然杀手(NK)细胞介导免疫,并按捺单核细胞的促炎细胞因子的发生。

 

  结果显现:承受泊马度胺(Pomalyst)单一医治的患者7.4%达到ORR.泊马度胺(Pomalyst)加低剂量地塞米松医治的患者中有29.2%显现ORR,应对持续时间中位数7.4个月。

 

  临床研讨证明,泊马度胺(Pomalyst)医治复发或难治性多发性骨髓瘤有用,而且有实验对其在其他血液系统疾病中的疗效进行了探究。该药可引起患者中性粒细胞削减、血小板削减等血液学毒性,以及腹泻、发热、深静脉血栓形成等非血液学毒性。

 

  印度版泊马度胺作用怎么样?印度版泊马度胺(Pomalyst)是仿制药,也是全球价格最便宜的一款。虽然是仿制药,但其药效与原研药相差无几,作用相同,而且相对于原研药价格较低,性价比较高。也因此成为许多患者的挑选。由于汇率浮动价格不固定,患者如果想要了解该药品的详细价格,或是想要海外购买Pomalyst(泊马度胺),能够向国内靠谱的海外医疗服务机构咨询。

How about the Indian version of Poomadomide? Pomalyst, the Indian version of the drug, is generic and the cheapest in the world. Although it is a generic drug, its effect is almost the same as the original drug, and the price is lower than the original drug, cost-effective. Therefore, it has become the choice of many patients. As the exchange rate floating price is not fixed, patients who want to know the detailed price of the drug, or want to buy Pomalyst overseas, can consult with reliable overseas medical service institutions in China.


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